Dr. Tenke has been the principal electrophysiologist of the Psychophysiology laboratory, Dept. Biopsychology
since the death of Sam Sutton. Through the years, and across projects, grants and collaborations, he has developed and implemented a number of ERP/EEG paradigms.
He has also been responsible for the training and oversight of technicians (data acquisition and preliminary processing), data analysis, the interpretation,
and writeup of research findings, and preparing grant applications.
Anatomical and Physiological Methods
Dr. Tenke is experienced in various physiological methods, particularly (but not exclusively) those related to electrophysiology. In addition to human EEGs and ERPs, he has worked with a number of species, including monkey, cat, rabbit and rat. He has surgical experience using both open and stereotaxic methods. He was also in charge of a lab section on the gross dissection of human brain specimens for a medical school class. Dr. Tenke has frequently applied his neuroanatomical, mathematical and programming expertise to the evaluation and study of the underlying generators of the EEG/ERP. Methods include dipole models, current source density analysis and component identification/ simplification using principal components analysis.
Dr. Tenke has developed software for computer systems of varied sizes and descriptions, ranging from mainframes (IBM and Xerox) through mid-size and mini computers (DEC Minc and PDP 11/34 ) and various microprocessor systems (including Commodore, TRS-80, Apple Macintosh and IBM standard PCs), as well as a number of specialized ERP analysis systems, including the Nicolet Med-80 and Pathfinder computers, and the BEAM system. He has had extensive experience with a number of programming languages and environments, ranging from machine language, assembler and C/C++ to FORTRAN, BASIC, MATLAB and BATCH. Much of Dr. Tenke's early programming experience was directed at real time task control and physiological data acquisition (including interrupt programming in assembler) for human and animal studies. Physiological measures have included EEG and ERP, pupillography, eye movement and plethysmography. Other applications developed by Dr. Tenke include programs for computing power spectra, signal coherence and transfer coefficients; for correction of ocular artifact from ERP/EEG (linear regression approach); for modeling; and for statistical analysis.
Dr. Tenke has had lifelong, hands-on experience in designing, building and repairing electronic devices. Among the specific hardware projects of relevance to neuroscience are: interfaces for ERP task control (eg., counters, timers, Schmidt triggers, parallel IO); auditory stimulus generator; hardware for sequencing, coding, and presenting electrical brain stimulation during EEG recordings in rats; threshold amplitude detectors; analog filters; various digital timers, counters and operational amplifiers circuits; and interfaces for a tactile perception study.
Training, Mentoring and Developing Techniques
Dr. Tenke has trained and mentored technicians, doctoral candidates, and postdoctoral researchers in the conduct of electrophysiological research. His work with Dr. Kayser has proven to be particularly fruitful. In an ongoing series of publications, they have developed new and powerful techniques for human scalp-recorded ERP and EEG data.
Collaborations with Other Departments
Dr. Tenke has developed and implemented EEG protocols for collaborators and trained their technical staff, but remains individually responsible for the analysis, interpretation, and publication of many collaborative findings.